We recommend you include the following information in your citation. Look below the item for additional data you may want to include.
Contact Owning Institution
All fields are required.
Request Text
Requests for a digital copy can be submitted through the Library, Special Collections (UC San Francisco) request system, Aeon.
Click the button below to submit your request. Please note that you will need to create an Aeon account or log in to your existing account.
Download Item
Please use this item responsibly. Check the rights information for this item to see if it has copyright restrictions. Note that even if the item is protected by copyright, you may be able to use it for educational, research, or other purposes. To learn more, read Calisphere's terms of use.
Do you need a bigger file? To obtain an alternate file type or higher resolution copy, please
contact the owning institution.
Copyrighted Transmission or reproduction of materials protected by copyright beyond that
allowed by fair use requires the written permission of the copyright owners. Works not in the public domain cannot be commercially exploited without permission of the copyright owner. Responsibility for any use rests exclusively with the user.
Description
Scope/Content: Dr. Jay Levy's thesis as a medical student at Columbia University. Biography/History: In 1962, as a medical student, Dr. Levy volunteered to join the laboratory of Dr. Herbert Rosenkranz to study a -state in bacteria called lysogeny, in which viruses silently infect bacteria and affect their function. That appeared to be a good model for silent cancer viruses. That research led to his discovery that the recently developed chemical drug hydroxyurea (HU) was unique in blocking DNA synthesis but not RNA synthesis. Lysogenic bacteria grown in the presence of HU became larger without any significant effect on their biological state. This observation, a sideline to the effect of viruses in lysogeny, did not show any effect on the virus in the bacteria.
Type
text
Identifier
MSS_2017_46_Levy_49_24
Language
English eng
Subject
Lysogeny Cancer Research Levy, Jay Columbia University. College of Physicians and Surgeons
If you're wondering about permissions and what you can do with this item, a good starting point is the "rights information" on this page. See our terms of use for more tips.
Share your story
Has Calisphere helped you advance your research, complete a project, or find something meaningful? We'd love to hear about it; please send us a message.
