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Description
Transition from 1D to 2D migration: regulation of cellular phenotype by ECM topography. Formation of multiaxial lamellae and cell spreading during the transition from 1D to 2D migration. 2D matrices were constructed by uniform coating with extracellular matrix (ECM). 1D surfaces were made by using a 2 photon confocal microscope to pattern a polyvinyl alchohol (PVA) coated coverslip. Following gluteraldehyde quenching, ECM proteins were absorbed onto the PVA surface. Movie is video 6 from JCB 2009, 184:481-490 Research Data Curation Program, UC San Diego, La Jolla, 92093-0175 (https://lib.ucsd.edu/rdcp) Doyle, Andrew D.; Wang, Francis W.; Matsumoto, Kazue; Yamada, Kenneth M. (2021). CIL:13161, Mus musculus, fibroblast. In Cell Image Library. UC San Diego Library Digital Collections. Dataset. https://doi.org/10.6075/J0M0445F
Type
image
Identifier
ark:/20775/bb10304991
Language
No linguistic content
Subject
Cell migration NIH/3T3 Substrate-dependent cell migration, cell attachment to substrate Cell Fibroblast Mus musculus Cell Image Library Group ID: 9565
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