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Description
Tem1 (green) constitutively targeted to spindle pole bodies in nud1-2 cells at the restrictive temperature still displayed problems positioning the spindle (this image shows a misaligned spindle, CIL #13873 shows an aligned spindle and CIL# 13874 shows a rebudded cell) typical of nud1-2, despite the fact that viability was restored. Nud1 is required for mitotic exit and constitutive targeting of Tem1 recovered the mitotic exit defect of nud1-2 cells. DAPI (blue) and differential interference contrast (DIC) image are also shown. Image is Fig 7F, middle panels, in J Cell Biol. (2011) 192: 599-614. Images in Fig 7 include CIL #13888, 13872, 13813, 13889, 13874. Research Data Curation Program, UC San Diego, La Jolla, 92093-0175 (https://lib.ucsd.edu/rdcp) Valerio-Santiago, Mauricio; Monje-Casas, Fernando (2021). CIL:13889, Saccharomyces cerevisiae. In Cell Image Library. UC San Diego Library Digital Collections. Dataset. https://doi.org/10.6075/J070805W
Type
image
Identifier
ark:/20775/bb12011832
Language
No linguistic content
Subject
Exit from mitosis Cell division Regulation of exit from mitosis GTPase activator activity Nucleotide binding Cell cycle GTPase activity Mitotic cell cycle spindle orientation checkpoint W303 Mitosis Small GTPase mediated signal transduction Protein binding Structural constituent of cytoskeleton Spindle pole body Cytoskeleton Cytoplasm Nuclear envelope Nucleus Saccharomyces cerevisiae Cell Image Library Group ID: 9034
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