Data from: Genetic characterization of outbred Sprague Dawley rats and utility for genome-wide association studies
Creator
Palmer, Abraham A
Contributor
Gonzales, Natalia M. Williams, April E. Flagel, Shelly B. Robinson, Terry E. Joyce, Elizabeth V. Maguire, Rachael J. McLeod, Africa M. St. Pierre, Celine L. Chitre, Apurva S.
Under copyright Constraint(s) on Use: This work is protected by the U.S. Copyright Law (Title 17, U.S.C.). Use of this work beyond that allowed by "fair use" or any license applied to this work requires written permission of the copyright holder(s). Responsibility for obtaining permissions and any use and distribution of this work rests exclusively with the user and not the UC San Diego Library. Inquiries can be made to the UC San Diego Library program having custody of the work. Use: This work is available from the UC San Diego Library. This digital copy of the work is intended to support research, teaching, and private study.
Rights Holder and Contact
UC Regents
Description
The data in this object comes from the publication titled “Genetic characterization of outbred Sprague Dawley rats and utility for genome-wide association studies”, authored by Gileta et al. The majority of the object is dedicated to the supplementary information (figures, tables, files) presented throughout the publication. However, this object also contains additional information beyond what is presented, including (1) a VCF file containing all raw SNP calls with dosage data in the original set of 4,625 Sprague Dawley rats, (2) filtered variants in BIM/BED/FAM format for each of the seven Sprague Dawley genetic subgroupings, and (3) summary files for the GWAS results for all 55 metric x training day combinations for all individual subgroups and their meta-analyses. Details on how these files were generated can all be found in the Methods section of the associated publication. This work was funded by the National Institute of Drug Addiction (NIDA; https://www.drugabuse.gov/) through R21 DA036672 (AAP; TER; SBF), P50 DA037844 (AAP; TER; SBF), and F31 DA039638-02 (AFG), as well as training grant T32 GM007197 (AFG) from the National Institute of General Medical Sciences (NIGMS; https://www.nigms.nih.gov/). Research Data Curation Program, UC San Diego, La Jolla, 92093-0175 (https://lib.ucsd.edu/rdcp) Gileta, Alexander F.; Fitzpatrick, Christopher J.; Chitre, Apurva S.; St. Pierre, Celine L.; Joyce, Elizabeth V.; Maguire, Rachael J.; McLeod, Africa M.; Gonzales, Natalia M.; Williams, April E.; Morrow, Jonathan D.; Robinson, Terry E.; Flagel, Shelly B.; Palmer, Abraham A. (2022). Data from: Genetic characterization of outbred Sprague Dawley rats and utility for genome-wide association studies. In Abraham A. Palmer Lab Research Data Collection. UC San Diego Library Digital Collections. https://doi.org/10.6075/J0XS5V8K
Type
dataset
Identifier
ark:/20775/bb5572228j
Language
English
Subject
Complex trait Quantitative trait locus (QTL) mapping Population structure Psychiatric genetics Rat Pavlovian condition approach Genome-wide association study (GWAS) Genotype by sequencing Meta-analysis Model system Behavioral trait mapping Addiction Sprague Dawley Harlan Charles River Laboratories
If you're wondering about permissions and what you can do with this item, a good starting point is the "rights information" on this page. See our terms of use for more tips.
Share your story
Has Calisphere helped you advance your research, complete a project, or find something meaningful? We'd love to hear about it; please send us a message.
