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Title
Data from: Genetic characterization of outbred Sprague Dawley rats and utility for genome-wide association studies
Creator
Palmer, Abraham A
Date Created and/or Issued
2011 to 2021
Contributing Institution
UC San Diego, Research Data Curation Program
Collection
Data from: Genetic characterization of outbred Sprague Dawley rats and utility for genome-wide association studies
Rights Information
Under copyright
Constraint(s) on Use: This work is protected by the U.S. Copyright Law (Title 17, U.S.C.). Use of this work beyond that allowed by "fair use" or any license applied to this work requires written permission of the copyright holder(s). Responsibility for obtaining permissions and any use and distribution of this work rests exclusively with the user and not the UC San Diego Library. Inquiries can be made to the UC San Diego Library program having custody of the work.
Use: This work is available from the UC San Diego Library. This digital copy of the work is intended to support research, teaching, and private study.
Rights Holder and Contact
UC Regents
Description
The data in this collection comes from the publication titled “Genetic characterization of outbred Sprague Dawley rats and utility for genome-wide association studies”, authored by Gileta et al. The majority of the collection is dedicated to the supplementary information (figures, tables, files) presented throughout the publication. However, this collection also contains additional information beyond what is presented, including (1) a VCF file containing all raw SNP calls with dosage data in the original set of 4,625 Sprague Dawley rats, (2) filtered variants in BIM/BED/FAM format for each of the seven Sprague Dawley genetic subgroupings, and (3) summary files for the GWAS results for all 55 metric x training day combinations for all individual subgroups and their meta-analyses. Details on how these files were generated can all be found in the Methods section of the associated publication.
This work was funded by the National Institute of Drug Addiction (NIDA; https://www.drugabuse.gov/) through R21 DA036672 (AAP; TER; SBF), P50 DA037844 (AAP; TER; SBF), and F31 DA039638-02 (AFG), as well as training grant T32 GM007197 (AFG) from the National Institute of General Medical Sciences (NIGMS; https://www.nigms.nih.gov/).
Research Data Curation Program, UC San Diego, La Jolla, 92093-0175 (https://lib.ucsd.edu/rdcp)
Gileta, Alexander F.; Fitzpatrick, Christopher J.; Chitre, Apurva S.; St. Pierre, Celine L.; Joyce, Elizabeth V.; Maguire, Rachael J.; McLeod, Africa M.; Gonzales, Natalia M.; Williams, April E.; Morrow, Jonathan D.; Robinson, Terry E.; Flagel, Shelly B.; Palmer, Abraham A. (2022). Data from: Genetic characterization of outbred Sprague Dawley rats and utility for genome-wide association studies. UC San Diego Library Digital Collections. https://doi.org/10.6075/J0XS5V8K
Type
Dataset
Language
English
Subject
Complex trait
Quantitative trait locus (QTL) mapping
Population structure
Psychiatric genetics
Rat
Pavlovian condition approach
Genome-wide association study (GWAS)
Genotype by sequencing
Meta-analysis
Model system
Behavioral trait mapping
Addiction
Sprague Dawley
Harlan
Charles River Laboratories

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