Under copyright Constraint(s) on Use: This work is protected by the U.S. Copyright Law (Title 17, U.S.C.). Use of this work beyond that allowed by "fair use" or any license applied to this work requires written permission of the copyright holder(s). Responsibility for obtaining permissions and any use and distribution of this work rests exclusively with the user and not the UC San Diego Library. Inquiries can be made to the UC San Diego Library program having custody of the work. Use: This work is available from the UC San Diego Library. This digital copy of the work is intended to support research, teaching, and private study.
Rights Holder and Contact
Lyons, Anne; Schmitt, Danielle; Mehta, Sohum; Zhang, Jin
Description
Caption: Watch an energy regulator on mitochondria, cellular powerhouses that go wherever energy is needed Mitochondria are the part of cells responsible for producing energy using the sugars we get from food and the oxygen we breathe. This energy we have readily available at any point is monitored by a protein called AMPK. If we don't have a lot of energy available, AMPK tells other parts of the cell to focus less on building and more on breaking things down to create more energy. In this image, a fluorescent sensor that can detect when AMPK is "talking" or "quiet" was attached to the mitochondria. With certain lower energy conditions, AMPK talks louder and we see even greater brightness from the sensor in our images. Understanding this conversation AMPK starts is important in studying energy-related diseases like diabetes and cancer. Research Data Curation Program, UC San Diego, La Jolla, 92093-0175 (https://lib.ucsd.edu/rdcp) Lyons, Anne; Schmitt, Danielle; Mehta, Sohum; Zhang, Jin (2022). Energy Worms. In Art of Science. UC San Diego Library Digital Collections. https://doi.org/10.6075/J00C4VZN
Type
image
Identifier
ark:/20775/bb5675451v
Language
No linguistic content
Subject
Art and science Mitochondria AMP-activated protein kinase (AMPK) Art of Science Contest - 2022
If you're wondering about permissions and what you can do with this item, a good starting point is the "rights information" on this page. See our terms of use for more tips.
Share your story
Has Calisphere helped you advance your research, complete a project, or find something meaningful? We'd love to hear about it; please send us a message.