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Description
TEM image of frozen hydrated soluble chromatin isolated from chicken erythrocyte nuclei and vitrified in low salt. Polynucleosomes adopt an irregular zigzag fiber conformation (a,b,k), and show a 'stem' motif. Similar features are seen in reconstituted polynucleosomes (c,d,f-i). However, if reconstitutes lack linker histone H5, the stem conformation is absent (c). See Fig 1 in J Bednar et al. 1998 Nucleosomes, linker DNA and linker histone form a unique structural motif that directs the higher-order folding and compaction of chromatin. Proc Natl Acad Sci USA 95:14173-14178. Research Data Curation Program, UC San Diego, La Jolla, 92093-0175 (https://lib.ucsd.edu/rdcp) Bednar, Jan; Horowitz, Rachel; Grigoryev, Sergei; Carruthers, Lenny; Hansen, Jeffrey; Koster, Abraham J.; Woodcock, Christopher (2021). CIL:39731, Gallus gallus gallus, erythrocyte. In Cell Image Library. UC San Diego Library Digital Collections. Dataset. https://doi.org/10.6075/J0R78D0P
Type
image
Identifier
ark:/20775/bb64573712
Language
No linguistic content
Subject
DNA packaging Cellular component organization at cellular level Chromatin Erythrocyte Nucleosome Heterochromatin Gallus gallus gallus Cell Image Library Group ID: 10715
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