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Dataset / Data from: Genome-Wide Association Study in 3,173 Outbred Rats Identifies Multiple Loci …

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Title
Data from: Genome-Wide Association Study in 3,173 Outbred Rats Identifies Multiple Loci for Body Weight, Adiposity, and Fasting Glucose
Creator
Chen, Hao
Flagel, Shelly B
Meyer, Paul
Palmer, Abraham A
Richards, Jerry
Robinson, Terry E
Solberg Woods, Leah C
Contributor
Chitre, Apurva S.
Bimschleger, Hannah
Garcia Martinez, Angel
George, Anthony
Holl, Katie
Horvath, Aidan
Hughson, Alesa
Palmer, Abraham A.
Han, Wenyan
King, Christopher P.
Lamparelli, Alexander
Martin, Connor
Polesskaya, Oksana
St. Pierre, Celine L.
Tripi, Jordan A.
Versaggi, Cassandra L.
Cheng, Riyan
Gileta, Alexander F.
Ishiwari, Keita
Wang, Tengfei
Gao, Jianjun
Date Created and/or Issued
2014 to 2020
Contributing Institution
UC San Diego, Research Data Curation Program
Collection
The Center for GWAS in Outbred Rats Database (C-GORD)
Rights Information
Under copyright
Constraint(s) on Use: This work is protected by the U.S. Copyright Law (Title 17, U.S.C.). Use of this work beyond that allowed by "fair use" or any license applied to this work requires written permission of the copyright holder(s). Responsibility for obtaining permissions and any use and distribution of this work rests exclusively with the user and not the UC San Diego Library. Inquiries can be made to the UC San Diego Library program having custody of the work.
Use: This work is available from the UC San Diego Library. This digital copy of the work is intended to support research, teaching, and private study.
Rights Holder and Contact
UC Regents
Description
The data in this object comes from the publication titled “Genome-Wide Association Study in 3,173 Outbred Rats Identifies Multiple Loci for Body Weight, Adiposity, and Fasting Glucose”, authored by Chitre et al. The majority of the object is dedicated to the phenotypic and genetic data presented throughout the publication. However, this object also contains additional information beyond what is presented, including (1) a genetic relatedness matrix generated from LD pruned set of genotypes, (2) Summary files for the GWAS results for all phenotypes, (3) Trait descriptions. Details on how these files were generated can all be found in the Methods section of the associated publication.
This work was supported by the National Institute on Drug Abuse (P50 DA037844) and the National Institute of Diabetes and Digestive and Kidney Diseases (R01 DK106386).
Research Data Curation Program, UC San Diego, La Jolla, 92093-0175 (https://lib.ucsd.edu/rdcp)
Chitre, Apurva S.; Polesskaya, Oksana; Holl, Katie; Gao, Jianjun; Cheng, Riyan; Bimschleger, Hannah; Garcia Martinez, Angel; George, Anthony; Gileta, Alexander F.; Han, Wenyan; Horvath, Aidan; Hughson, Alesa; Ishiwari, Keita; King, Christopher P.; Lamparelli, Alexander; Versaggi, Cassandra L.; Martin, Connor; St. Pierre, Celine L.; Tripi, Jordan A.; Wang, Tengfei; Chen, Hao; Flagel, Shelly B.; Meyer, Paul; Richards, Jerry; Robinson, Terry E.; Palmer, Abraham A.; Solberg Woods, Leah C. (2022). Data from: Genome-Wide Association Study in 3,173 Outbred Rats Identifies Multiple Loci for Body Weight, Adiposity, and Fasting Glucose. In The Center for GWAS in Outbred Rats Database (C-GORD). UC San Diego Library Digital Collections. https://doi.org/10.6075/J0Q240F0
Type
dataset
Identifier
ark:/20775/bb9156620z
Language
English
Subject
Genetics
Task: Multiclass classification
Task: Regression
Complex trait
Algorithm: Unsupervised learning
Obesity
Rat
Algorithm: Supervised learning
Adiposity
Genome-wide association study (GWAS)
Task: Dimensionality reduction
Task: Clustering
Heterogeneous stock (HS) rats
Task: Feature extraction
Task: Classification
Task: Ranking
Genotype by sequencing (GBS)
Task: Binary classification
Task: Anomaly detection

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