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Description
In the absence of boi (boi[e] mutant), Hedgehog (Hh, red) is redistributed from apical cells to the extracellular space of the local follicle stem cell niche (CIL# 13744, 13745). Expression of Boi in apical cells relocalizes Hh to apical cells (CIL#13746). Apical cell expression of Ihog, which also binds Hh directly, rescues Hh localization in the boi[e] mutant (this image; boi[e]; ihog[EP]/+; babGal4/+). Germ cells are identified with anti-Vasa (blue). Image is Fig 3E in J Cell Biol. 2010. 191: 943-952. Images in Fig 3 include CIL# 13744, 13745, 13746, 13747, 13748. Research Data Curation Program, UC San Diego, La Jolla, 92093-0175 (https://lib.ucsd.edu/rdcp) Hartman, Tiffiney R.; Zinshteyn, Daniel; Schofield, Heather K.; Nicolas, Emmanuelle; Okada, Ami; O'Reilly, Alana M. (2021). CIL:13748, Drosophila melanogaster, germ line cell, follicle cell, germ line stem cell, follicle stem cell. In Cell Image Library. UC San Diego Library Digital Collections. Dataset. https://doi.org/10.6075/J0MK6BKX
Type
image
Identifier
ark:/20775/bb08598767
Language
No linguistic content
Subject
RNA binding Ovarian follicle cell development Germ-line cyst formation Boi[e] Protein binding Morphogen activity Cysteine-type endopeptidase activity Cell adhesion Positive regulation of smoothened signaling pathway Positive regulation of hh target transcription factor activity Smoothened signaling pathway ATP-dependent helicase activity Patched binding MRNA 3'-UTR binding Germ-line stem cell division Positive regulation of translation Germarium-derived egg chamber formation Germ line stem cell Follicle cell Cytoplasmic membrane-bounded vesicle Extracellular region Germ line cell P granule Follicle stem cell Endocytic vesicle Drosophila melanogaster Cell Image Library Group ID: 8382
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