Andersen, Jens S Blow, J. Julian Hunter, Christopher J Khoudoli, Guennadi A McAinsh, Andrew D McClelland, Sarah E Porter, Iain M Swedlow, Jason R
Contributor
Andersen, Jens S. Blow, J. Julian Hunter, Christopher J. Khoudoli, Guennadi A. McAinsh, Andrew D. McClelland, Sarah E. Porter, Iain M. Swedlow, Jason R.
Under copyright Constraint(s) on Use: This work is protected by the U.S. Copyright Law (Title 17, U.S.C.). Use of this work beyond that allowed by "fair use" or any license applied to this work requires written permission of the copyright holder(s). Responsibility for obtaining permissions and any use and distribution of this work rests exclusively with the user and not the UC San Diego Library. Inquiries can be made to the UC San Diego Library program having custody of the work. Use: This work is available from the UC San Diego Library. This digital copy of the work is intended to support research, teaching, and private study.
Rights Holder and Contact
UC Regents
Description
Z-focal series of HeLa cell at metaphase stained for DNA (blue), phospho-Ser92-MAK (mitotic centromere-associated kinesin) (red), and Aurora B (green). Phosphorylation of MCAK is reduced in Bod1siRNA cells. Cells were transfected with control (this image) or Bod1 (CIL: 13378) siRNA. After 72 h, cells were treated with monastrol for 3 h and released into media containing MG132 for 1 h before fixing. Cells were stained for total mitotic centromere-associated kinesin (MCAK) population. MCAK localizes to the inner centromere in its phosphorylated form but concentrates at kinetochores in its dephosphorylated state. Research Data Curation Program, UC San Diego, La Jolla, 92093-0175 (https://lib.ucsd.edu/rdcp) Porter, Iain M.; McClelland, Sarah E.; Khoudoli, Guennadi A.; Hunter, Christopher J.; Andersen, Jens S.; McAinsh, Andrew D.; Blow, J. Julian; Swedlow, Jason R. (2021). CIL:13379, Homo sapiens. In Cell Image Library. UC San Diego Library Digital Collections. Dataset. https://doi.org/10.6075/J0F47MV5
Type
image
Identifier
ark:/20775/bb1303540j
Language
No linguistic content
Subject
HeLa S3 Chromosome organization Mitosis HEC1 Phosphorylated MCAK Chromosome, centromeric region DNA Nuclear chromosome Homo sapiens Cell Image Library Group ID: 11195
If you're wondering about permissions and what you can do with this item, a good starting point is the "rights information" on this page. See our terms of use for more tips.
Share your story
Has Calisphere helped you advance your research, complete a project, or find something meaningful? We'd love to hear about it; please send us a message.
