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Description
Off-axis patterns perturb uniaxial migration, while 1D lines promote conversion to fibrillar migration. Effects of encountering a perpendicular fibrillar pattern during fibrillar migration (top) and conversion of 2D to 1D migration. 2D matrices were constructed by uniform coating with extracellular matrix (ECM). 1D surfaces were made by using a 2 photon confocal microscope to pattern a polyvinyl alchohol (PVA) coated coverslip. Following gluteraldehyde quenching, ECM proteins were absorbed onto the PVA surface. Movie is video 7 from JCB 2009, 184:481-490 Research Data Curation Program, UC San Diego, La Jolla, 92093-0175 (https://lib.ucsd.edu/rdcp) Doyle, Andrew D.; Wang, Francis W.; Matsumoto, Kazue; Yamada, Kenneth M. (2021). CIL:13162, Mus musculus, fibroblast. In Cell Image Library. UC San Diego Library Digital Collections. Dataset. https://doi.org/10.6075/J01Z434Z
Type
moving image
Identifier
ark:/20775/bb22591796
Language
No linguistic content
Subject
Cell migration NIH/3T3 Substrate-dependent cell migration, cell attachment to substrate Fibroblast Cell Mus musculus Cell Image Library Group ID: 9565
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