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Description
Hedgehog (Hh, red) is transcribed in apical cells of the Drosophila wild-type germarium (CIL# 13755 and this image). In the absence of boi (boi[e] mutant), Hh protein is redistributed from apical cells to the extracellular space of the local follicle stem cell niche (CIL# 13745), but Hh transcription is still in apical cells (CIL# 13754). Hh transcription is demonstrated by the Hh-lacZ reporter and follicle cells are highlighted using anti-Fas-3 (green). Image is Supplemental Figure S3A in J Cell Biol. 2010. 191: 943-952. Research Data Curation Program, UC San Diego, La Jolla, 92093-0175 (https://lib.ucsd.edu/rdcp) Hartman, Tiffiney R.; Zinshteyn, Daniel; Schofield, Heather K.; Nicolas, Emmanuelle; Okada, Ami; O'Reilly, Alana M. (2021). CIL:13755, Drosophila melanogaster, germ line cell, follicle cell, germ line stem cell, follicle stem cell. In Cell Image Library. UC San Diego Library Digital Collections. Dataset. https://doi.org/10.6075/J069728G
Type
image
Identifier
ark:/20775/bb3351367x
Language
No linguistic content
Subject
Ovarian follicle cell development Morphogen activity Protein binding Homophilic cell adhesion Patched binding Positive regulation of smoothened signaling pathway Germ-line stem cell division Positive regulation of hh target transcription factor activity Cysteine-type endopeptidase activity Germ line stem cell Germ line cell Plasma membrane Cytoplasmic membrane-bounded vesicle Endocytic vesicle Follicle stem cell Extracellular region Follicle cell Drosophila melanogaster Cell Image Library Group ID: 8382
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