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Description
This image combines total internal reflection microscopy (TIRF) of mCerulean-actin (blue) with photoactivation localization microscopy (PALM) image of tdEos-vinculin (red) and Dronpa-paxillin (green). Vinculin and paxillin are organized into focal adhesions at the ends of actin bundles. A higher magnification of several adhesion complexes (CIL 38651) clearly shows that vinculin and paxillin are segregated into interlocking microdomains within focal adhesions. Bar is 2 microns. Image made available by Catherine and James Galbraith and corresponds to Figure 5 in PNAS U S A. 2007 Dec 18;104(51):20308-13. Research Data Curation Program, UC San Diego, La Jolla, 92093-0175 (https://lib.ucsd.edu/rdcp) Shroff, Hari; Galbraith, Catherine G.; Galbraith, James A.; White, Helen; Gillette, Jennifer; Olenych, Scott; Davidson, Michael W.; Betzig, Eric (2021). CIL:38652, Homo sapiens, fibroblast. In Cell Image Library. UC San Diego Library Digital Collections. Dataset. https://doi.org/10.6075/J0N58K1K
Type
image
Identifier
ark:/20775/bb41706499
Language
No linguistic content
Subject
Molecular organization Foreskin fibroblast Actin cytoskeleton Focal adhesion Vinculin Fibroblast Paxillin Homo sapiens Cell Image Library Group ID: 9553
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