Under copyright Constraint(s) on Use: This work is protected by the U.S. Copyright Law (Title 17, U.S.C.). Use of this work beyond that allowed by "fair use" or any license applied to this work requires written permission of the copyright holder(s). Responsibility for obtaining permissions and any use and distribution of this work rests exclusively with the user and not the UC San Diego Library. Inquiries can be made to the UC San Diego Library program having custody of the work. Use: This work is available from the UC San Diego Library. This digital copy of the work is intended to support research, teaching, and private study.
Rights Holder and Contact
UC Regents
Description
Boi (green) and Hedgehog (Hh, red) are expressed in apical cells of the Drosophila wild-type germarium (CIL#13744). In the absence of boi (boi[e] mutant), Hh is redistributed from apical cells to the extracellular space of the local follicle stem cell niche (CIL# 13745). Expression of Boi in apical cells relocalizes Hh to apical cells (CIL#13746), but expression of Boi[∆FN1] that lacks the Hh-binding domain fails to rescue Hh localization (this image; boi[e]; UAS-Boi[∆FN1]/+;babGal4/+). Image is Fig 3D in J Cell Biol. 2010. 191: 943-952. Images in Fig 3 include CIL# 13744, 13745, 13746, 13747, 13748. Research Data Curation Program, UC San Diego, La Jolla, 92093-0175 (https://lib.ucsd.edu/rdcp) Hartman, Tiffiney R.; Zinshteyn, Daniel; Schofield, Heather K.; Nicolas, Emmanuelle; Okada, Ami; O'Reilly, Alana M. (2021). CIL:13747, Drosophila melanogaster, germ line cell, follicle cell, germ line stem cell, follicle stem cell. In Cell Image Library. UC San Diego Library Digital Collections. Dataset. https://doi.org/10.6075/J0513X0N
Type
image
Identifier
ark:/20775/bb47848258
Language
No linguistic content
Subject
Boi[e] Cysteine-type endopeptidase activity Cell adhesion Smoothened signaling pathway Patched binding Germ-line stem cell division Morphogen activity Positive regulation of smoothened signaling pathway Protein binding Positive regulation of hh target transcription factor activity Ovarian follicle cell development Germ line cell Extracellular region Follicle stem cell Follicle cell Germ line stem cell Cytoplasmic membrane-bounded vesicle Endocytic vesicle Drosophila melanogaster Cell Image Library Group ID: 8382
If you're wondering about permissions and what you can do with this item, a good starting point is the "rights information" on this page. See our terms of use for more tips.
Share your story
Has Calisphere helped you advance your research, complete a project, or find something meaningful? We'd love to hear about it; please send us a message.
