Under copyright Constraint(s) on Use: This work is protected by the U.S. Copyright Law (Title 17, U.S.C.). Use of this work beyond that allowed by "fair use" or any license applied to this work requires written permission of the copyright holder(s). Responsibility for obtaining permissions and any use and distribution of this work rests exclusively with the user and not the UC San Diego Library. Inquiries can be made to the UC San Diego Library program having custody of the work. Use: This work is available from the UC San Diego Library. This digital copy of the work is intended to support research, teaching, and private study.
Rights Holder and Contact
UC Regents
Description
Localization of cross-linking proteins in fibroblast cytoskeleton. Fluorescence microscopy and corresponding intensity profiles human 356 fibroblast lamellipodia double stained with TRITC-phalloidin (red) and ABP-280 (green). The protein/actin ratio at the leading edge of the lamellipodium is medium for ABP-280. Immuno-EM of the cell edge (CIL 34926) or interior (CIL 34929) of cytochalasin D treated human 356 fibroblasts stained with ABP-280 primary antibody and 10-nm gold-conjugated secondary antibody reveals ABP-280 at filament crossovers in the cell interior. Image corresponds to Figure 5b and b' from J Cell Biol. 1999 May 31;145(5):1009-26. Research Data Curation Program, UC San Diego, La Jolla, 92093-0175 (https://lib.ucsd.edu/rdcp) Svitkina, Tatyana M.; Borisy, Gary G. (2021). CIL:34923, Homo sapiens, fibroblast. In Cell Image Library. UC San Diego Library Digital Collections. Dataset. https://doi.org/10.6075/J05D8QG4
Type
image
Identifier
ark:/20775/bb58771087
Language
No linguistic content
Subject
Cellular localization Human 356 ABP-280 Fibroblast Actin cytoskeleton Lamellipodium Homo sapiens Cell Image Library Group ID: 9875
If you're wondering about permissions and what you can do with this item, a good starting point is the "rights information" on this page. See our terms of use for more tips.
Share your story
Has Calisphere helped you advance your research, complete a project, or find something meaningful? We'd love to hear about it; please send us a message.
