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Description
Behaviors of the microtubule anchoring factor RFP-LL5α (red) and microtubules (green) in living epithelial cells undergoing random migration. During the time-lapse imaging, the cells divided into two daughter cells. Cortical patches of RFP-LL5α appear when cells become attached to the glass substrate, but disappear when the cells become detached at the onset of cell division. The patches reappear soon after the cells adhere to the glass again. Overall findings from this publication showed that signaling from laminin-integrin associations plays a role in attaching microtubule plus ends to the epithelial basal cell cortex. This is the original data file for Video 4 from J Cell Biol (2010) 189 (5):901-917. Research Data Curation Program, UC San Diego, La Jolla, 92093-0175 (https://lib.ucsd.edu/rdcp) Hotta, Azusa; Kawakatsu, Tomomi; Nakatani, Tomoya; Sato, Toshitaka; Matsui, Chiyuki; Sukezane, Taiko; Akagi, Tsuyoshi; Hamaji, Tomoki; Grigoriev, Ilya; Akhmanova, Anna; Takai, Yoshimi; Mimori-Kiyosue, Yuko (2021). CIL:12287, Homo sapiens, epithelial cell. In Cell Image Library. UC San Diego Library Digital Collections. Dataset. https://doi.org/10.6075/J0WW7GD9
Type
image
Identifier
ark:/20775/bb8470826z
Language
No linguistic content
Subject
Establishment or maintenance of apical/basal cell polarity Cell-substrate adhesion Cell division MCF 10A Epithelial cell migration Cell cortex part Microtubule Epithelial cell Homo sapiens Cell Image Library Group ID: 8194
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