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Description
Boi (green) and Hedgehog (Hh, red) are expressed in apical cells of the Drosophila wild-type germarium (CIL# 13744). In the absence of boi (boi[e] mutant), Hh is redistributed from apical cells to the extracellular space of the local follicle stem cell niche (CIL# 13745). Expression of Boi in apical cells in the boi[e] mutant (boi[e]; UAS-Boi/+; babGal4/+) rescues Hh localization to apical cells (this image). However, expression of a Boi mutant lacking the Hh-binding domain does not (CIL# 13747). Nuclei are labeled (DRAQ5, blue). Image is Fig 3C in J Cell Biol. 2010. 191: 943-952. Images in Fig 3 include CIL# 13744, 13745, 13746, 13747, 13748. Research Data Curation Program, UC San Diego, La Jolla, 92093-0175 (https://lib.ucsd.edu/rdcp) Hartman, Tiffiney R.; Zinshteyn, Daniel; Schofield, Heather K.; Nicolas, Emmanuelle; Okada, Ami; O'Reilly, Alana M. (2021). CIL:13746, Drosophila melanogaster, germ line cell, follicle cell, germ line stem cell, follicle stem cell. In Cell Image Library. UC San Diego Library Digital Collections. Dataset. https://doi.org/10.6075/J0D21WBG
Type
image
Identifier
ark:/20775/bb87097761
Language
No linguistic content
Subject
Cysteine-type endopeptidase activity Positive regulation of smoothened signaling pathway Cell adhesion Morphogen activity Protein binding Smoothened signaling pathway Patched binding Germ-line stem cell division Positive regulation of hh target transcription factor activity Ovarian follicle cell development Cytoplasmic membrane-bounded vesicle Germ line stem cell Germ line cell Extracellular region Endocytic vesicle Follicle cell Follicle stem cell Drosophila melanogaster Cell Image Library Group ID: 8382
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