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Image / CIL:37141, Rattus, pancreatic acinar cell

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Title
CIL:37141, Rattus, pancreatic acinar cell
Creator
Palade, George E
Contributor
Palade, George E.
Date Created and/or Issued
1966-10-12
Contributing Institution
UC San Diego, Research Data Curation Program
Collection
Cell Image Library
Rights Information
Under copyright
Constraint(s) on Use: This work is protected by the U.S. Copyright Law (Title 17, U.S.C.). Use of this work beyond that allowed by "fair use" or any license applied to this work requires written permission of the copyright holder(s). Responsibility for obtaining permissions and any use and distribution of this work rests exclusively with the user and not the UC San Diego Library. Inquiries can be made to the UC San Diego Library program having custody of the work.
Use: This work is available from the UC San Diego Library. This digital copy of the work is intended to support research, teaching, and private study.
Rights Holder and Contact
UC Regents
Description
Transmission electron micrograph of exocytosis taken from the rat pancreas. Images such as these indicated that secretory granules closely and selectively approach the apical membrane of the pancreatic acinar cell where exocytosis takes place, fuse with the apposed membrane, and release the content of secretory proteins into the acinar lumen without broaching the intracellular environment. The resulting omega figure is transitory, suggesting that the excess granule membrane is retrieved/recycled. Note the actin coat around the newly inserted granule membrane. Image made available by James D. Jamieson and the Department of Cell Biology, Yale University School of Medicine.
Research Data Curation Program, UC San Diego, La Jolla, 92093-0175 (https://lib.ucsd.edu/rdcp)
Palade, George E. (2021). CIL:37141, Rattus, pancreatic acinar cell. In Cell Image Library. UC San Diego Library Digital Collections. Dataset. https://doi.org/10.6075/J0416VPM
Type
image
Identifier
ark:/20775/bb9187742z
Language
No linguistic content
Subject
Exocytosis
Pancreatic acinar cell
Secretory granule
Secretory granule membrane
Rattus
Cell Image Library Group ID: 9989

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