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Description
This is a view of apical domains of two adjacent hepatocytes in the guinea pig liver, showing the junctional complexes that attach cells to one another. The bile canaliculus (BC) is defined by the cell membranes (CM) of two adjacent liver cells. At the level of the tight junctions (also known as zonula occludens, ZO) the intercellular spaces are sealed, thereby preventing leakage of bile from the canaliculus. Two adherens junctions (also known as zonula adherens, ZA) and two desmosomes (D) are seen distal (relative to the canaliculus) to each tight junction. Glycogen (gly) particles are apparent in the cytoplasm of the liver cells.This was part of the first description of tight junctions and junctional complexes between epithelial cells from many tissues. Identical unlabeled image available as CIL# 7598. Image published as Figure 13 in Farquhar and Palade, 1963. Research Data Curation Program, UC San Diego, La Jolla, 92093-0175 (https://lib.ucsd.edu/rdcp) Palade, George E. (2021). CIL:7599, Cavia porcellus, hepatocyte. In Cell Image Library. UC San Diego Library Digital Collections. Dataset. https://doi.org/10.6075/J0P26WT4
Type
image
Identifier
ark:/20775/bb8334283d
Language
No linguistic content
Subject
Canalicular bile acid transport Zonula adherens Tight junction Desmosome Hepatocyte Cavia porcellus Cell Image Library Group ID: 9508
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