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Description
Apoptotic cells produce and transmit the bioactive lipid sphingosine-1-phosphate (S1P) during extrusion. This set of images shows that extrusion is blocked, as well as accumulation of S1P around the dying cell, by SKI II, which blocks conversion of sphingosine to S1P. The apoptotic condensed nucleus is in blue, the actin-myosin ring at the basolateral surface is in red and S1P is in green. Research Data Curation Program, UC San Diego, La Jolla, 92093-0175 (https://lib.ucsd.edu/rdcp) Gu, Yapeng; Forostyan, Tetyana; Sabbadini, Roger; Rosenblatt, Jody (2021). CIL:37911, Homo sapiens, epithelial cell. In Cell Image Library. UC San Diego Library Digital Collections. Dataset. https://doi.org/10.6075/J0V986PS
Type
image
Identifier
ark:/20775/bb89147164
Language
No linguistic content
Subject
Protein binding Apoptotic process HBE1 Actomyosin structure organization Cortical actin cytoskeleton Epithelial cell Nucleus Homo sapiens Cell Image Library Group ID: 9650
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