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Dataset / CIL:13592, Mus musculus, myoblast

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Title
CIL:13592, Mus musculus, myoblast
Creator
Band, Mark
Chen, Jie
Drnevich, Jenny
Ge, Yejing
Sun, Yuting
Zhao, Yong
Date Created and/or Issued
2021
Contributing Institution
UC San Diego, Research Data Curation Program
Collection
Cell Image Library
Rights Information
Under copyright
Constraint(s) on Use: This work is protected by the U.S. Copyright Law (Title 17, U.S.C.). Use of this work beyond that allowed by "fair use" or any license applied to this work requires written permission of the copyright holder(s). Responsibility for obtaining permissions and any use and distribution of this work rests exclusively with the user and not the UC San Diego Library. Inquiries can be made to the UC San Diego Library program having custody of the work.
Use: This work is available from the UC San Diego Library. This digital copy of the work is intended to support research, teaching, and private study.
Rights Holder and Contact
UC Regents
Description
The C2C12 cell line, a mouse myoblast line, was used here to study the regulatory factors in myogenic differentiation. After cultured in differentiation medium for 3 days, these cells differentiated into myotubes (Green) containing multiple nuclei (Blue). The C2C12 cells stably expressing FLAG-tagged rapamycin-resistant, kinase-inactive (RR/KI) mTOR were induced to differentiation in the presence of 50nM rapamycin for 3 days. The C2C12 cells differentiated, but arrested at the nascent myotube stage. This image is the control of different treatments in Figure 9B from JCB 189: 1157-1169, 2010. See also CIL: 13593, 13594, 13601.
Research Data Curation Program, UC San Diego, La Jolla, 92093-0175 (https://lib.ucsd.edu/rdcp)
Sun, Yuting; Ge, Yejing; Drnevich, Jenny; Zhao, Yong; Band, Mark; Chen, Jie (2021). CIL:13592, Mus musculus, myoblast. In Cell Image Library. UC San Diego Library Digital Collections. Dataset. https://doi.org/10.6075/J0RX99S1
JCB 189: 1157-1169, 2010 https://www.ncbi.nlm.nih.gov/pubmed/?term=20566686
Type
Dataset
Language
No linguistic content; Not applicable
Subject
MTOR inhibition
Myoblast fusion
C2C12
Nucleus
Muscle myosin complex
Myoblast
Mus musculus
Cell Image Library Group ID: 8288

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