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Image / CIL:13599, Mus musculus, skeletal muscle cell

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Title
CIL:13599, Mus musculus, skeletal muscle cell
Creator
Band, Mark
Chen, Jie
Dmevich, Jenny
Ge, Yejing
Sun, Yuting
Zhao, Yong
Date Created and/or Issued
2021
Contributing Institution
UC San Diego, Research Data Curation Program
Collection
Cell Image Library
Rights Information
Under copyright
Constraint(s) on Use: This work is protected by the U.S. Copyright Law (Title 17, U.S.C.). Use of this work beyond that allowed by "fair use" or any license applied to this work requires written permission of the copyright holder(s). Responsibility for obtaining permissions and any use and distribution of this work rests exclusively with the user and not the UC San Diego Library. Inquiries can be made to the UC San Diego Library program having custody of the work.
Use: This work is available from the UC San Diego Library. This digital copy of the work is intended to support research, teaching, and private study.
Rights Holder and Contact
UC Regents
Description
Mouse hind limb tibialis anterior (TA) muscles were injected with BaCl2 followed by daily systemic administration of rapamycin (Rap) starting 7 days after injury. The animals were sacrificed at different days, and the injured muscles were dissected and cryosectioned followed by hematoxylin (blue) and eosin (pink to red) staining. This image shows the regeneration of muscle tissue fourteen days after the injury with daily systemic administration of Rap from day 7 to day 13 and a single dose of adenovirus expressing follistatin was injected into the injured TA muscle on day 7. The growth inhibition of myofibers by Rap was rescued by recombinant follistatin expression. Myofibers were stained by eosin in red and nuclei were stained by hematoxylin in blue. This image corresponds to Fig 10B from JCB 189: 1157-1169, 2010. See also CIL: 13595, 13596, 13597, 13598, and 13600.
Research Data Curation Program, UC San Diego, La Jolla, 92093-0175 (https://lib.ucsd.edu/rdcp)
Sun, Yuting; Ge, Yejing; Dmevich, Jenny; Zhao, Yong; Band, Mark; Chen, Jie (2021). CIL:13599, Mus musculus, skeletal muscle cell. In Cell Image Library. UC San Diego Library Digital Collections. Dataset. https://doi.org/10.6075/J0ST7NJJ
JCB 189: 1157-1169, 2010 https://www.ncbi.nlm.nih.gov/pubmed/?term=20566686
Type
image
Language
No linguistic content; Not applicable
Subject
MTOR inhibition
Myoblast fusion involved in skeletal muscle regeneration
Skeletal muscle cell
Nucleus
Mus musculus
Cell Image Library Group ID: 8415

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