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Description
Expression of WT PINK1-YFP (green) does not induce mitochondrial translocation of mCherry-Parkin (red) in PINK1 knock-out mouse embryonic fibroblasts (PINK1 KO MEFs). Transfected PINK1 KO MEFs were treated with DMSO for 3 hrs. Live cell imaging was performed on an LSM510 Meta (Carl Zeiss, Inc) with a 63x 1.4 NA oil differential interference contrast Plan Apo objective. Image contrast and brightness were adjusted in the LSM image browser (Zeiss). This image corresponds to Supplemental Figure S1c, top left row of J Cell Biol, 191: 933-942, 2010. Images in Supplemental Figure S1c include CIL#s 13725, 13726, 13727, 13728. Research Data Curation Program, UC San Diego, La Jolla, 92093-0175 (https://lib.ucsd.edu/rdcp) Jin, Seok Min; Lazarou, Michael; Wang, Chunxin; Kane, Lesley A.; Narendra, Derek P.; Youle, Richard J. (2021). CIL:13726, Mus musculus, fibroblast. In Cell Image Library. UC San Diego Library Digital Collections. Dataset. https://doi.org/10.6075/J0P26WVK J Cell Biol, 191: 933-942, 2010. https://www.ncbi.nlm.nih.gov/pubmed/?term=21115803
Type
Dataset
Language
No linguistic content; Not applicable
Subject
Protein phosphorylation Ubiquitin protein ligase binding Intracellular protein kinase cascade Response to stress Protein binding Zinc ion binding Protein ubiquitination involved in ubiquitin-dependent protein catabolic process Ubiquitin-protein ligase activity C3HC4-type RING finger domain binding ATP binding Protein K48-linked ubiquitination Mitochondrion degradation Calcium-dependent protein kinase activity Protein K63-linked ubiquitination Magnesium ion binding Protein serine/threonine kinase activity Cytosol Fibroblast Nucleus Mitochondrial outer membrane Mitochondrion Mitochondrial inner membrane Mus musculus Cell Image Library Group ID: 7051
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